After reading the patient information leaflet I was hesitant to take medication today. Stopped AA & CAL3D immediately!! It was becoming clear to me at this point that activity brought on my symptoms, and at that time it was extreme activity a session at the gym, a long bike ride, a strenuous walk. Im 61 and after a long history of fractures (mostly sports related) and a recent wrist fracture from a fall, I had a DXA scan and have Oseopenia. I hate taking meds and wonder if I should stop Alendronic acid. It may put you at risk of jaw bone damage. I started reading this because after being diagnosed with breast cancer part of my ongoing treatment is Letrozole plus Alendronic Acid. Alendronate is also used to treat Paget's disease of bone. Took my 1st AA 2 days ago, since then Ive had constant stomachache, feel exhausted, and tired, and shivering. Hi I have been on alendronic acid for 7 months I was worried about side effects but have been ok but have noticed a weakness in muscles and am really stiff in mornings and if I sit down even for a short while. Inhibiting osteoclast function, as bisphosphonates do, lessens bone resorption. Hi everyone.I am new to this forum.I started taking Alendronic acid for the first time yesterday.I have had a bone density scan which shows i have oesteoporosis.I am 59 years old,considered myself quite fit until last June,I have read the side effects of these tablets and what other people have put about them.I am quite scared about taking anymore.I felt fine yesterday after taking mu first . Hi. Read on a page recently that the manufacturers of this drug have been sued in Canada by 1200 odd people and won 27.5 millionso why hasnt this been reviewed here. Whenever Ive mentioned it to my GP, its sort of brushed away. In rare cases, alendronic acid may cause a serious allergic reaction ( anaphylaxis ). I also had pain/soreness behind the eyes and a niggling headache for 48 hours. Alendronate is the drug we know as Fosamax. I have had 7 weeks off work with a fractured wrist and another week off with feeling poorly due to AA (with no pay as Im a self employed carer) and need to feel fully fit before returning to work. For oral liquid medicine, use the dosing syringe to measure one unit (70 mg in 100 ml) of oral solution and take it once a week. When i DID start researching, after being on these meds for about a year I decided the risk just wasnt worth the POSSIBLE gain and stopped taking it. Now on Alendronic 70 weekly. Do not just stop taking alendronic acid without your doctors approval. She takes Alendronic Acid every week for a year and a half now for her osteoporosis. If recommended to be taken twice a day, you should have it during lunchtime and dinnertime. She has had none of the horrible side effects mentioned in these posts so it must work for some people. I feel very tired and my bones are much more painful now. There is nothing I can do to stop the shoulder pain, and lower jaw pain, or the chills I get. Next morning extreme pain in my back and kidney area. Looking back over the past four years of this journey, I realised that whenever I took any other tablets my symptoms worsened dramatically. Bisphosphonates: atrial fibrillation - GOV.UK The Royal Osteoporosis Society website is very detailed and useful, with info on exercise you should do more of it which must be weight bearing more so than just walking and promote balance. Hey Ive been diagnosed with polymialgia rheumatica too i was prescribed predisolone vit d evacol and now AA Im not having any side effects from it yet but reading all of these comments Im worrying about wether I should take the alendronic acid Ive only taken two up to now but have had no problem with it yet It scares you a bit, Hi I have just been precribed alendronic acid I have not taken it yet as I have had a bad cold. I have taken 2 in total. Its recommended to take it on an empty stomach first thing in the morning. I asked how we would know if it wasnt working, and his reply was that it would be having an effect on my bones after six months and the next scan results would indicate an increased bone density, or not. I decided to stop for a few months following my retirement as I was going travelling for 3 months. Small blisters on various areas of my body. I have had osteoarthritis for twenty years, and was diagnosed as as having osteopenia 7 years ago. It was so frightening my partner called for an ambulance and I was taken to the local hospital, where they hid me in a side room to let me sit and jerk in private. PDF NHS Trust How to take Alendronic Acid and Calcium and Vitamin D - OUH I slept restless, my shoulders began to hurt. Im not really happy with the idea of another pill so asked what would happen if I didnt take them and she said I dont know ! Alendronic acid (bisphosphonate) is a prescription medication used to help your bones stay as strong as possible. The Odteoporosis Society were great adn adviced me to see a specialist. However, it usually takes 6-12 months of ongoing medication to get its full benefit. I still do not feel right and have added pain, although a bit better than it was. Brand Names Adrovance, Binosto, Fosamax, Fosamax Plus D, Fosavance Generic Name Alendronic acid DrugBank Accession Number DB00630 Background In the morning (Wednesday) I was not able to zip my jeans, brush my hair or other daily activities. The NHS Dentist has ben very negative and created time consuming visits which are difficult for me to arrange because I have decreasing mobility because of MS. No one my GP or the dentist recommended by my GP have given me no warning about the serious side effects of having dental extractions while taking Aldronic Acid. Many thanks for all your comments re Alendronic Acid, these have been most helpful in my decision to take this drug. Pharmaceutical drugs are just about making money and not curing people. For more about osteoporosis and medication, see Fragile Doctors: Iatroporosis. Drinking alcohol for about two standards per day may increase your risk of bone fractures. Both. Burning chest pain, sore throat and pains all over. Then one day my body turned to chaos. Already taking Adcal D3 and steroids. However Im convinced that its the AA tablet and am very scared to take another! I am disappointed in my GP who recommended a NHS Dentist in Melcome Avenue, Wemouth. Alendronic acid and teeth - Osteoporosis - Inspire I do wonder if all of this is as a result of being on Seroxat for so long. The side effect possibilities worry me. Tablets the gift that keeps giving, I have just had a DXA scan (following a wrist fracture) and it came back I have really bad osteoporosis. She was given physiowhat a mistake that was.After fighting to get her x rayed, the doctor phoned her and said that I was right and she needed a hip replacement, her hips had crumbled away. It hurts to walk on my feet. In 2002 I discovered via the internet that I wasn't desperately ill with an anxiety disorder that only Seroxat could fix. I took it on Tuesday. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Subscribe to newsletter If I apply pressure to the back of my neck, my neck pain still hurts really bad, but I can move my neck. My crown became wobbly and fell out . I have now been off Alendronic acid for two weeks or so, and at the moment im not noticing very much improvement. I am not in your age group Jane bit I can appreciate Yor feeling left out. Stopping this medication means maintaining your bone health and density through lifestyle and diet. Avoid taking it if you have esophageal or throat conditions. . Ostopenia and had a high risk of a fracture. Your doctor might recommend you take other drugs 30 minutes after taking alendronic acid. Im not going to take another one and just hope these pains gradually wear off. This pain was far worse than the pain I experience withOsteoporosis! Bottom Line. Gary Curd. I wonder if it might be something that could help you Ive attached the link to the video below. This was on top of my usual activity levels. Do not lie down for at least 30 minutes after taking medicine. When my doctor told me emphatically that I couldnt build my bones with diet and exercise alone, I reluctantly said ok, but I want to take strontium. It usually takes 6-12 months of taking alendronic acid to support your bones. Yet we women know when something is not right we seek help only to be fobbed off by stupid replys from doctors only to get rid of us . Warning to anyone who might be taking Alendronic acid 70 ml tablets for osteoporosis ! Im sure they will sound familiar. This full head pain is extremely bad. From day one my tummy was not happy & after 8 weeks I suddenly became severely constipated (Literally overnight !!!) Does anyone know if theres a link between the 2 drugs or if theres a suitable alternative? In addition, you should cut down on your alcohol intake, stop smoking, do strength training and supplement your body with calcium and vitamin D3, K2, and magnesium regularly. I have gone downhill and increased weight. Alendronic Acid - Take a break! | Birdshot Uveitis Society Reading all above, i think i will put myself on a little break, just to see if there is a difference in my condition overall. Even a couple of paracetamol would make me ill. And of course I was already taking Seroxat, albeit a very small amount. Nothing too spectacular to report. Yes and i stopped taking them my stomach was so bad i could only chest breathe. Firstly, the potential gastric problems, secondly osteonecrosis of the jaw, and thirdly the suggestion that the quality of the bone created by the drug is not as good as normal bone. There is a fine balance struck in order to treat symptoms without curing, so your symptoms are only abated when you take drugs, but if you die, then obviously they make no more money. Your body naturally breaks down old bones and replaces them with new bone tissues to support your skeletal system throughout life. Food and beverages (eg, mineral water, coffee, tea, or juice) will decrease the amount of alendronate absorbed by the body. Can you give me the name of this book, I too am struggling with whether to go down the road of alendronic acid. Jan. Alendronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. I should have been warned of this side affect. Hi Ive had AA and it made me feel terrible! I had had a two year bone scan and been told that my bone density had increased, so as far as I was concerned, the drug was working and all was well in that particular area. How Alendronic Acid Destroyed My Life - Meds Safety My mom who is 76 has taken 7 tablets, she stopped due to pain in her hips legs and groin. Common Fosamax Side Effects I dont think there is enough information from doctors/nurses to explain about Osteoporosis to patients. These may increase the risk of damage to your jaw bone. I am aldo taking Calcio with vitamin-D September 2020 Diagnosed with PMR & prescribed Prednisolone + ADCAL3D +Alendronic Acid. By this time my body was still, so I went home feeling scared and utterly distraught. It belongs to a group of drugs called bisphosphonates, which are the most commonly used treatment for people with osteoporosis. Alendronate (Oral Route) Side Effects - Mayo Clinic The dentist recommend my mom to have all teeth in the lower jaw removed (some are already loose) and get denture. I have now vowed NOT to take another tablet, after all at my age, I feel I have nothing to lose! My ears was hurting. I had to stop immediately and was plunged in to full blown menopause, which has been hell ever since. Newly diagnosed: Hi everyone I'm 57 and have - Bone Health I reported the effect the drug had on me to the MHRA. I have been on Sertraline 70mg for a few years and as I have asthma my inhaler has been changed to Beclmetasome 100/6. I just want to feel better. This is fascinating. bones Archives - The Heart And Brain I have been taking A.A for about 9/10 months. This is a vile drug dangerous and should be pulled from market to protect any future victims. That is, when the hospital said I had osteoporosis. But first, you should learn more about osteoporosis. Sunday night started feeling unwell, sleepless night, sweating and chills. I was told that it was very uncommon what happened to me, and it was my choice to take it again next week or not. Alendronic acid contains an active ingredient, alendronate sodium, a bisphosphonate. Ive only just started on the AA but since my run in with Metoclopramide Im scared to take any drugs now. Thanks. Alendronate (alendronic acid) - Royal Osteoporosis Society reduce the risk of fractures in people with osteoporosis. Ive not taken many of the Adcal, and havent yet taken any Alendronic Acid, and to be honest Im now thinking about not talking it at all, as the possible side effects are really worrying me. Which has brought me here as I googled info on this medication. This led me to think I was in Seroxat withdrawal; so convinced, in fact, I was of this that I asked my doctor to contact GSK to see if they had changed the formulation in some way, as I had made no change to my dose. I was told I had osteoporosis in 2004 and was put on Fosamax for about 6 months after which I was switched to Actonel. Your dentist will have heard of it and will ensure that you have any treatment done before you start. They are ok and work fine for first few years ! Hi Rowena. What an awful time you are having my sympathy goes out to you. Been given Alendronic acid 10mg tablet which I have to take daily. Since taking alendronic, I have had difficulty in running and doing all the workout I was doing. Alendronic acid and teeth extraction My mother saw the dentist recently because of gum infection. Terms|Privacy, Research Forum for Enduring Sexual Dysfunction, https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA, https://www.druglawsuitsource.com/canada-fosamax-lawsuits-settled/. I walked home very gingerly with the dog and later phoned my doctor Felicity Hi everyone I was put on alendronic about 25years ago after scan, had bad time painful joins,palpitations,pains in my chest was that bad they thought I was having heart attack,doctors dismiss as stress. I will make sure I get it. Hello I am 66 and like many of you am hating taking this drug, I had breast cancer 4 years ago,so am still taking Anastrosil as it was Hormone related,which in turn apparantly helped causing bone density loss, so ws then diagnosed with osteopenia In case of severe allergic reactions and poisoning on your first dose, please call your doctor or emergency help immediately. Went to ER did EKG and blood work. Do not take this drug if you have mild to severe kidney problems. 4 days after my 6th dose, I woke up in the night with right hip pain. In addition, previous side effects were swellings and wealds all over, itching and bloatedness. Bisphosphonates are a class of osteoporosis drugs such as Boniva (ibandronate), Fosamax (alendronate), Actonel (risedronate) and Reclast (zoledronic acid). Dosage instructions, including remaining upright for at least 30 minutes and taking with a full glass of water, must be strictly followed. alendronic acid has destroyed my life - hullabaloo.tv I woke up, called my doctor to make sure it was safe to take with a few broken ribs, and I was told yes. I had been suffering with a terrible burning tongue for eight months and I also had aching legs, this burning tongue I put down to the gallstones I have got. If I apply pressure to my temples, my headache lessens. Ive been reading all the posts on this forum THINK I might stop altogether does anyone else get these symptoms. My lower teeth started getting loose and getting cavities to the point where , in 2011 I had to have the last remaining 6 lower teeth pulled and dentures made. Store the tablet, oral solution, or oral effervescent form of alendronic acid as directed in its packaging. they mask the crumbling bones within and only show the outer bone growth, I have decided I really dont want to take these any more but wonder if there are side effects. How Alendronic Acid works Alendronic Acid is a bisphosphonate. Cholesterol-lowering medications -- A class of medications known as bile acid sequestrants (including cholestyramine, colestipol, and colesevelam), used to treat high cholesterol, may interfere with normal calcium absorption and increase the loss of calcium in the urine. She sent me to a specialist for a second opinion and he said take it. Im 62. Stopping and seeing if the symptoms resolve for most drugs is the best way to prove a link some problems with some drugs may take time more time than you expect but will resolve but some may also be permanent. I too am very healthy woman 67, play golf dance swim walk, so I was upset to be told I had osteoporosis. I was intrigued as my doctor had said specifically not to! Its bad enough living with PBC and all that entails for the rest of my life, but to go through what all of you good people have gone through NO WAY DANNO! 20 mile house bernadette 0533 929 10 81; best time to visit kodiak island info@reklamcnr.com; grateful dead from the vault box set caner@reklamcnr.com; athens high school basketball roster reklamcnr20@gmail.com I also went willingly and happily to the gym twice a week and did weekly pilates. Continue reading for a comprehensive list of adverse effects. The NHS say. I appear to be ding well on them so I am told along with calcium and Vit D supplements. I have even had to report my concern and disappointment and lack of care by both my GP and Dentist. Im wondering how you feel now, a year after stopping the drug, have your symptoms improved? It begins as minor dental problems and can escalate to permanent jaw damage. There are over 200 million people worldwide who have osteoporosis. Hi, Ive just discovered this site. I better print your reviews kind people & put them before my GP & the Liver Consultant who suggested bisphosphonates in the first place!! 6.5 Nature and contents of . Another problem that really concerns me is that my teeth feel rough, as though the surface is eroding. Im considering ringing the hospital myself to see if I can have one done. If you were prescribed to take 10 mg of alendronic acid, swallow one whole tablet daily. Blood test in November showed a underactive thyriod and am taking Levothyronine 25mg. Alendronic acid | C4H13NO7P2 - PubChem This makes them at high risk of developing osteopenia or osteoporosis. In the meantime her teeth fell outliterally fell outwhat on earth was happening. Very useful thread this thanks everyone. I also ate one energice bar. I compared it with strontium ranelate, which was the drug my sister was taking, and the strontium appeared to have better results. This has come to light since I collapsed in the shower , after complaining of thigh bone pain for over 2 years ! I expect only the shareholders are enthusiastic about it! Side effects include heartburn, upset stomach, nausea, diarrhea and constipation, as well as stomach, muscle, joint and bone pain. Any advice would be greatly appreciated. Alendronic acid and teeth extraction : r/askdentists - Reddit Store below 25C. I would demand one straight away. Alendronate Uses, Side Effects & Warnings - Drugs.com I suggested, because of the Seroxat link, that I might be sent to a Seroxat specialist. Again i had another Dexa scan 2 years ago and it was found i have oesteoporosis in the spine which i feel very worried about it. With this condition, your bones become thin and weak, and break easily. Despite the doctor's assurances that it wasn't addictive, I became addicted. Had another car ride, but then it flared up again, sometimes I limped all morning. But I just couldnt describe it as you have. Theres little research if alendronic acid is safe for breastfeeding moms. I am also diabetic 2 (no drugs diet only) coeliac (wheat and gluten free. Its been a nightmare for four weeks weeks. I got a book on osteoporosis from the library and it explained against taking alendronic acid and any other medication that contain biphosphates. but from the start have not felt well, stabbing pains dental probs,aching joints,My dentist referred me to a specialist to have 3 teeth removed,but i lost it in the chair so scared ! muscles ache, no energy, depression. That was the last tablet I took of that drug. who told me it could be one of many things. No tablet is worth taking if no quality of life. Feel quite worried reading all these comments but thoughts Id just let people know that my 90 year old mother has been taking AA plus Adcal for about 8 years after two falls in which her wrists were broken ( falls due to hypotension caused by drug she was currently taking. I have taken them for 5+ years and after some research now I discover that the scans can give false readings, i.e. I cannot say specifically that they have caused me any problems. She decided to come off the Alendronic AcidShe really has gone downhill. Im 59 and have a very physical job which involves a lot of walking, and I was told by a clinician when I first started treatment that it cant help the spine anyway! If I apply pressure on my face in front of my ear, the ear pain lessens. Ulcers or erosions of your esophagus and gut, which include symptoms like severe heartburn, trouble and pain when swallowing, Bone death or damage on your jaw with symptoms like painful or swollen gums, loosening of teeth, numbness and heavy feeling in your jaw, and mouth sores, Unusual bone breaks in your hip and leg bones which is indicated by a dull, aching pain in your hips, groin, or thighs, Damage of bones in your inner ear with symptoms ear pain, ear discharge, or infection, Swelling in the eyes which have signs like blurred vision, painful or red eyes. cant belive my GP gave me these awful tablets . This study is a randomized, double-blind, placebo-controlled 2-year study. The method comprises the steps of reacting a compound of formula I with H 3 PO 3 wherein R is an imido group and R 1 is selected from the group consisting of chloro, bromo, iodo, fluoro, hydroxy, amino, OR 2 or OC(O)R 2 , wherein R 2 is C 1 -C 12 alkyl, C 1 -C 12 cycloalkyl or C 1 -C 12 aryl; and then reacting the . Im going to stop taking Alendronic acid. Ive just been prescribed AA but having read all the posts on this site have decided not to start taking it. Eventually, I Started Pilates and regular walking. Soil degradation is a process in which the value of the land and its biophysical environment is affected by a combination of human actions and non-natural . Hi everyone I thought my diziness and muscle ache and a light pain in my abdomen when i took Alendronic Acid was just me, now reading all the comments I can see it is a common theme.