Lozano, P., Flores, D., Martinez, S., Artigues, I., Rimbau, E. M., and Gomez, F. Upper limb ischemia induced by chronic licorice ingestion. 2 in the perioperative stage of laparoscopic cholecystectomy]. Why Black Licorice Can Make Your Heart Skip - Cleveland Clinic Arch.Pharm Res 2012;35(11):1945-1952. Sakamoto S, Kudo H, Suzuki S, et al. Double-blind, placebo-controlled, randomized, pilot clinical trial of ImmunoGuard--a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. Antiviral Res 1987;7(2):99-107. Baba, M. and Shigeta, S. Antiviral activity of glycyrrhizin against varicella-zoster virus in vitro. Postgrad Med 2017;129(3):329-31. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. What Are The Side Effects Of Licorice? - Dietary Supplement Products View abstract. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. Digestion 2004;69:45-52. View abstract. View abstract. Yorgun, H., Aksoy, H., Sendur, M. A., Ates, A. H., Kaya, E. B., Aytemir, K., and Oto, A. Brugada syndrome with aborted sudden cardiac death related to liquorice-induced hypokalemia. View abstract. View abstract. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. Exp Neurol 1997;146:518-25. View abstract. Ir J Med Sci 2016;185(4):945-7. [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. View abstract. Sheehan M, Rustin MHA, Atherton DJ, et al. CJEM 2010;12(3):224-225. 6. 2020;2020:8401239. Feng Z, Xu J, He G, et al. Licorice can decrease how quickly the body breaks down corticosteroids. Dobbins, K. R. and Saul, R. F. Transient visual loss after licorice ingestion. Prospective study]. Motherwort, Peony, Dong Quai, Lady's Mantle, Licorice, and Rose, Fennel, Alfalfa. View abstract. Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis. Ned.Tijdschr Geneeskd. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. J Clin Ther Med 1999;15:499-523. View abstract. 2020;50:102401. Deglycyrrhizinated liquorice in aphthous ulcers. View abstract. View abstract. View abstract. American Herbal Products Association's Botanical Safety Handbook, Second Edition. If you take birth control pills along with peony, use an additional form of birth control such as a condom. Asian Medical Journal 1984;26(7):423-438. Lancet 1992;340:13-17. . Ann Pharmacother 2003;37(6):836-838. Lancet 2-10-1973;1(7798):294-295. Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. Morris DJ, Davis E, Latif SA. Kumada T, et al. Turpie AG, Runcie J, Thomson TJ. View abstract. Mol.Nutr Food Res 2011;55(2):318-327. Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis -- double blind trial. View abstract. Phytother Res 2009;23(2):246-250. Hsiang, C. Y., Hsieh, C. L., Wu, S. L., Lai, I. L., and Ho, T. Y. Inhibitory effect of anti-pyretic and anti-inflammatory herbs on herpes simplex virus replication. Vestn.Dermatol.Venerol. View abstract. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. Licorice roots can be consumed directly to get relief from cough and sore throat. Am J Chin Med 2003;31:445-53. . Hajiaghamohammadi, A. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. View abstract. Astragalus may be safe when used orally and appropriately. J Biol Response Mod 1985;4:551-84. Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. View abstract. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. N Engl J Med 1990;322:849-50. Drugs & Vitamins . OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. View abstract. J Clin Endocrinol Metab 2003;88:2384-92. Antiviral Res 12-11-1988;10(6):289-298. View abstract. View abstract. J Hepatol 1994;21:601-9. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. [The nature of an anticoagulant isolated from peonies in the central zone of Russia]. Minerva Med 2008;99(1):91-94. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. View abstract. Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. However, taking too much licorice root may cause side effects. 1991;78(1-2):1-6. View abstract. Lancet 2000;355(9198):134-138. Life Sci 2005;78:413-20 . White peony root is very much essential and used in Chinese medicine because of its medicinal properties. J Contemp.Dent Pract. Asl, M. N. and Hosseinzadeh, H. Review of pharmacological effects of Glycyrrhiza sp. 2017 Sep;31(9):1330-1340. Chatterjee, N., Domoto-Reilly, K., Fecci, P. E., Schwamm, L. H., and Singhal, A. WebMD does not provide medical advice, diagnosis or treatment. 5-10-2004;208(1):89-94. Peony root might decrease the amount of phenytoin in the body. Ann Mtg Digestive Disease Week 1999 May. View abstract. View abstract. Ma, X. F. [Experimental and clinical studies on the treatment of pulmonary heart disease and pulmonary hypertension with Paeonia lactiflora]. A Rutgers expert discusses how eating black licorice can affect your health. View abstract. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Goto, F., Asama, Y., and Ogawa, K. Sho-saiko-to-ka-kikyo-sekko as an alternative treatment for chronic tonsillitis to avoid surgery. 2001;21(7):501-503. Purnak, T., Ozaslan, E., Beyazit, Y., and Haznedaroglu, I. C. Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper. View abstract. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. Mu Y, Zhang J, Zhang S, et al. View abstract. It has an effect similar to aldosterone. View abstract. Zhonghua Yi Xue Za Zhi 1983;63:477-81. View abstract. Akbari N, Asadimehr N, Kiani Z. Gut 1973;14(9):711-715. Monitor your blood pressure closely. Scand.J Gastroenterol. All rights reserved. Isr J Dent Sci 1989;2(3):153-157. Anon. 2004;24(12):1084-1086. View abstract. View abstract. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. Psychoneuroendocrinology. 2020 Dec;58(1):352-356. View abstract. Man SC, Li XB, Wang HH, et al. Hum Exp Toxicol 2012;31(12):1295-1298. Int Hepatol Comm 1997;233-238. Beretta-Piccoli, C., Salvade, G., Crivelli, P. L., and Weidmann, P. Body-sodium and blood volume in a patient with licorice-induced hypertension. Natural Fertility Treatment Options: Copesthetic Health J Altern Complement Med. The herb has also been studied for use in canine atopic dermatitis along with white peony (Paeonia lactiflora) and licorice (Glycyrrhiza glabra). Blood Press 2009;18:192-5. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. West J Med 1997;167(3):184-185. Electronic Code of Federal Regulations. View abstract. Lozenge-induced hypermineralcorticoid state--a unique case of licorice lozenges resulting in hypertension and hypokalemia. Proanthocyanidins, flavonoids, tannins, polysaccharides, and paeoniflorin are all considered to contribute to the medicinal activity of various forms of peony. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Crean, A. M., Abdel-Rahman, S. E., and Greenwood, J. P. A sweet tooth as the root cause of cardiac arrest. 2003;84(1):85-89. 1979;14(5):605-607. Jia, Y. This can increase the effects and side effects of corticosteroids. Ai, M., Yamaguchi, T., Odaka, T., Mitsuhashi, K., Shishido, T., Yan, J., Seza, A., and Saisho, H. Objective assessment of the antispasmodic effect of shakuyaku-kanzo-to (TJ-68), a Chinese herbal medicine, on the colonic wall by direct spraying during colonoscopy. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. There are studies with assisted nutrients to expedite healing and mitigate side effects of hormone imbalances associated with IVF/IUI discussed below. Am J Chin Med 1996;24:165-8. View abstract. Licorice is an herb that grows in parts of Europe and Asia. Paeoniflorin's. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. 2013 Jun;22(2):173-8. N Engl J Med 1991;325:1223-7. View abstract. [RETRACTED]. Information from this source is evidence-based and objective, and without commercial influence. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. Yang HO, Ko WK, Kim JY, Ro HS. View abstract. Immediately afterwards, Teacher Liu looked at her, picked up her paper, and said, Student Zhou Xiaotong, this time I ll give you a warning. 1987;(10):46-48. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. Yamaguchi, H., Kidachi, Y., Kamiie, K., Noshita, T., Umetsu, H., and Ryoyama, K. Glycyrrhetinic acid induces anoikis-like death and cytoskeletal disruption in the central nervous system tumorigenic cells. A comparison of carbenoxolone sodium and deglycyrrhizinated liquorice in the treatment of gastric ulcer in the ambulant patient. Removes excess melanin: Licorice extract brightens the skin in another way, too. Yu C, Fan X, Li Z, Liu X, Wang G. Efficacy and safety of total glucosides of paeony combined with acitretin in the treatment of moderate-to-severe plaque psoriasis: a double-blind, randomised, placebo-controlled trial. 2000;20(3):173-175. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. View abstract. In an ovarietctomized model, oral administration of a combination of white peony and licorice increased DHEA and serum estrogen concentration. As I've all but cut out alcohol, I've tended to drink this tea before going to bed and sometimes during the day. Immunopharmacology 1999;41(3):169-181. A randomized, crossover comparison of herbal medicine and bromocriptine against risperidone-induced hyperprolactinemia in patients with schizophrenia. J Cancer Res Ther. Roussak NJ. WebMD does not provide medical advice, diagnosis or treatment. Steroids 2004;69(11-12):763-766. Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. Hinoshita F, Ogura Y, Suzuki Y, et al. Goultschin, J., Palmon, S., Shapira, L., Brayer, L., and Gedalia, I. An open study of 100 women with uterine fibroids showed that peony reduced the size of . Koo YK, Kim JM, Koo JY, et al. Allergic contact dermatitis to Glycyrrhiza inflata root extract in an anti-acne cosmetic product. Costa, A., Moises, T. A., Cordero, T., Alves, C. R., and Marmirori, J. A., Braun, T. M., and Jacobson, J. J. Mamgain RK, Gupta M, Mamgain P, et al. Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. Sigurjonsdottir, H. A., Manhem, K., Axelson, M., and Wallerstedt, S. Subjects with essential hypertension are more sensitive to the inhibition of 11 beta-HSD by liquorice. Oral Dis 2012;18(1):32-39. J Clin Psychopharmacol 2008;28(3):264-370. Chang GH, Lin YS, Hsu KH, et al. View abstract. A. Although some people believe that peony tea is the tea with the lowest caffeine levels, actually peony tea has a high caffeine level, as much as 5%. World J Gastroenterol 2-7-2006;12(5):760-764. View abstract. Mol Cell Endocrinol. View abstract. View abstract. Licorice that has the active ingredient of glycyrrhiza can have serious side effects. Dying for a cup of tea. View abstract. Mol Nutr Food Res 2006;50(11):1080-1086. Eur J Pharmacol 11-7-2005;524(1-3):111-119. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. Lee YS, Lorenzo BJ, Koufis T, et al. Davis EA, Morris DJ. Neth J Med 2005;63:119-20. [Peony tincture in the complex treatment of allergic dermatoses]. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Exp Med Surg 1969;27:411-20. A systemic review and meta-analysis of the clinical efficacy and safety of total glucosides of peony combined with methotrexate in rheumatoid arthritis. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. Eur J Pharmacol 1981;72:219-25.. View abstract. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. Ital.J Neurol.Sci 1997;18(4):217-220. Mechanism of anti-inflammatory action of glycyrrhizin: effect on neutrophil functions including reactive oxygen species generation. Cancer Lett. 2005;25(6):540-542. A preliminary open trial on interferon stimulator (SNMC) derived from Glycyrrhiza glabra in the treatment of subacute hepatic failure. Therapeutic Research Faculty 2020. Part 182 -- Substances Generally Recognized As Safe. Bisogni V, Rossi GP, Cal LA. Evid Based Complement Alternat Med 2016;2016:8292486. Licorice Root - Health Encyclopedia - University of Rochester Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. Journal of Clinical Therapeutics Medicine. View abstract. Peony might change how quickly the liver breaks down these medications. View abstract. View abstract. Lee, S. J., Lee, I. S., and Mar, W. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. Licorice is available in many different types of products, including candies, lozenges, teas, chewing, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Side effects in people after breathing tube removal. Clin Rheumatol. Drug Metab Dispos 2015;43(7):1147-53. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. Apparantly it's the one most important thing that shouldn't mix with Prednisolone and it makes withdrawal symptoms much worse. View abstract. J Ethnopharmacol. White Peony: Fertility Herb Ally The effects of licorice containing diphenhydramine solution on recurrent aphthous stomatitis: A double-blind, randomized clinical trial. Information from this source is evidence-based and objective, and without commercial influence. Da Nagao, Y., Sata, M., Suzuki, H., Tanikawa, K., Itoh, K., and Kameyama, T. Effectiveness of glycyrrhizin for oral lichen planus in patients with chronic HCV infection. J Gastroenterol Hepatol 1999;14(11):1093-1099. Anti Erection Pill. Pharm Biol 2021;59(1):1276-1285. Lancet 2-10-1979;1(8111):319. View abstract. [Treatment of refractory polycystic ovary syndrome by bushen huoxue method combined with ultrasound-guided follicle aspiration]. Fitoterapia 2004;75:45-9.. View abstract. The treatment of human cancer with agents prepared from bovine cartilage. The dose of your warfarin might need to be changed. An evaluation of the efficacy of licorice gargle for attenuating postoperative sore throat: a prospective, randomized, single-blind study. Taking peony along with estrogen might increase the effects and side effects from estrogen. View abstract. Zhang YD, Lorenzo B, Reidenberg MM. But not everyone will have the side . Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. J Hum Hypertens 1995;9:345-8. How Much Is Too Much? View abstract. White Peony is technically named Peonia lactiflora, and in Chinese, it is named Bai Shao. 1994;14:207-9, 195. . Association of emblica, licorice and belides as an alternative to hydroquinone in the clinical treatment of melasma. J Gastroenterol 1996;31(5):691-695. Ancient Chinese medicine unlocks new possibilities for - YaleNews View abstract. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . But, she survived . View abstract. View abstract. Because licorice has a hormone-like effect, it can relieve excessive gastric acid secretion. The Magical Root Angelica Sinensis - GaneshaSpeaks J Am Coll.Nutr 2007;26(3):209-218. Taking peony along with medications that also slow blood clotting might increase the risk of bruising and bleeding. 1986;6(12):714-6, 707. Guo TL, Zhou XW. View abstract. The chemicals in licorice are thought to . An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. Anonymous. Middle East J Anaesthesiol. View abstract. Kim YR, Nam SH. Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. Lee, C. K., Park, K. K., Lim, S. S., Park, J. H., and Chung, W. Y. Phytother.Res. Liu J. Part 2: Effect of glycyrrhizic acid on the course of illness]. J Clin Psychopharmacol 2016;36(6):572-9. Licorice can decrease potassium levels. A., Ziaee, A., and Samimi, R. The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial. (yatmunpnai mi) - Nephron 2002;90:240. View abstract. Biol Pharm Bull 2007;30(11):2191-2195. Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. Badr, A. E., Omar, N., and Badria, F. A. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. J Ethnopharmacol 2004;94:339-44. . Planta Med 1991;57(2):119-121. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. Int Urol Nephrol. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. Fugh-Berman, A. Herb-drug interactions. Sigurjonsdottir HA, Franzson L, Manhem K, et al. After lab testing, the Cheng team found that Huang Qin Tang had a high inhibitory property against the debilitating side effects of a chemotherapy drug called CPT-11 (later approved as irinotecan), including diarrhea, nausea, and vomiting. Hattori, M., Sakamoto, T., Kobashi, K., and Namba, T. Metabolism of glycyrrhizin by human intestinal flora. J Ethnopharmacol 2002;81:101-4.. View abstract. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. View abstract. Hidden Risks of Black Licorice | Rutgers University View abstract. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. Altern Med Rev 1999;4(3):178-188. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707. Am J Chin Med 2003;31:445-53. . The 54-year-old man was in a fast food . 1. Kimura Y, Okuda H, Okuda T, and et al. View abstract. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11. Dong quai Information | Mount Sinai - New York SOLARAY White Peony Root Extract | 60 VegCaps - amazon.com BMJ Case Rep 2012;2012. Ito, M., Nakashima, H., Baba, M., Pauwels, R., De Clercq, E., Shigeta, S., and Yamamoto, N. Inhibitory effect of glycyrrhizin on the in vitro infectivity and cytopathic activity of the human immunodeficiency virus [HIV (HTLV- III/LAV)]. View abstract.